Monkeypox Weekly Update

Up to 6 September 2022, in 43 countries and areas in the European region, a total of 23,196 cases of monkeypox have been reported to the health authorities European Center for Disease Prevention and Control (ECDC) and the World Health Organization. health (WHO), which represents an increase of 833 cases since last week[1].

Situation in the European region

The first known case dates from March 7, 2022 and was identified by a retrospective test on a residual sample. The first date of onset of symptoms was reported on April 3, 2022. The majority of cases were between 31 and 40 years old (9,113/22,960 – 40%) and were male (22,633/22,947 – 98.6%). Of the 9,682 male cases whose sexual orientation was known, 97% identified themselves as men who have sex with men. Of the cases with known HIV status, 37% (3,406/9,274) were HIV-positive. The majority of cases had rash (10,889/14,241–76.5%) and systemic symptoms such as fever, fatigue, muscle aches, vomiting, diarrhea, chills, sore throat or headache (9,705/14,241 – 68%). 638 cases were hospitalized (6%), including 212 who required clinical care. Five cases were admitted to the intensive care unit, three of whom died of monkeypox. To date, 87 cases have been reported to be healthcare workers, of which three cases had occupational exposure. In all three cases, healthcare workers were wearing the recommended personal protective equipment, but were exposed to body fluids while collecting samples.

Epidemiological situation in Luxembourg

Until September 7, 2022 inclusive, 54 cases of monkeypox have been detected in Luxembourg, which represents an increase of 1 case since last week. So far all the cases detected are male, with an average age of 37 years. Three cases were hospitalized for a short time and have meanwhile been discharged from hospital. The other epidemiological and clinical characteristics of cases detected in Luxembourg are very similar to cases reported at European level.

Vaccination against monkeypox for certain people at risk began at the National Service for Infectious Diseases (Tel.: 4411 3129 for appointment) on August 16, 2022. Last week, vaccination was also offered at the dispensary. DropIn for sex workers.

Until September 7, 2022, 527 people have been vaccinated: 522 people have received a first dose and 5 people a second dose.

Adaptation of the vaccination schedule

The recommendation of the Higher Council for Infectious Diseases of August 24, 2022 provides for the administration of a single dose to people who have received a previous vaccination against smallpox with a live 1st or 2nd generation vaccine (people born before 1977 or with a typical scar vaccination in the arm). [2] In these cases, a single dose will therefore be given in the future. Patients who do not fall into this category will continue to receive two doses of the vaccine.

Sanitary recommendations from the Health Department

The Department of Health recalls that it is important to protect yourself against the virus and to avoid risky situations in order to limit the spread of the virus. Infected people should be isolated and avoid contact with other people, cover lesions and pimples and practice hand hygiene. Among the protective measures, it is advisable to reduce the number of sexual partners and not to share personal effects with infected people or who have been in contact with infected people (bed linen, towel, razor, etc.) .

[1] https://monkeypoxreport.ecdc.europa.eu/

[2] https://sante.public.lu/dam-assets/fr/espace-professionnel/recommandations/conseil- Maladies-infectieuses/variole-singe/20220824-csmi-avis-mva-bn-id-nbre-de-doses- vf.pdf

Communicated by the Ministry of Health

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